Oncology Articles & Guides
In-depth educational content covering key concepts in modern cancer treatment, from drug mechanisms to clinical trial interpretation. These guides complement our tumor-specific data by providing broader context on the therapeutic approaches documented across PipelineEvidence.
PFS vs. OS: What Cancer Trial Endpoints Actually Mean for Patients
What is the difference between progression-free survival and overall survival? A guide to PFS, OS, DFS, ORR, and how the FDA uses them for approval...
Hazard Ratios Explained: What HR 0.70 Actually Means for Cancer Patients
What does a hazard ratio of 0.70 actually mean? This guide explains HRs, confidence intervals, and p-values in plain language with oncology examples...
How to Read a Kaplan-Meier Survival Curve: A Visual Guide for Oncology
A practical guide to reading KM curves — the axes, median survival, censoring marks, curve separation patterns, and the number-at-risk table...
Precision Medicine in Oncology: From Molecular Profiling to Targeted Treatment
How molecular profiling and genomic testing are transforming cancer treatment by matching patients with therapies targeting their tumor's specific gen...
Antibody-Drug Conjugates: The Guided Missiles of Cancer Therapy
Learn how antibody-drug conjugates (ADCs) deliver chemotherapy directly to cancer cells, the science behind their design, and why they are reshaping t...
How to Read a Clinical Trial Listing: A Practical Guide
A practical guide to understanding clinical trial listings on ClinicalTrials.gov, including trial phases, endpoints, eligibility criteria, study desig...
From Lab to Bedside: How New Cancer Drugs Get Approved
An overview of the cancer drug development process from preclinical research through FDA approval, including clinical trial phases, regulatory pathway...
Understanding Cancer Immunotherapy: How Checkpoint Inhibitors Work
An in-depth guide to checkpoint inhibitors — the immunotherapy drugs that have transformed cancer treatment. Learn how PD-1, PD-L1, and CTLA-4 inhibit...